Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p317 | (1) | WCRB2014

Analysis of marsupial ZP: molecular and phylogenetic approach

Nicolas C Moros , Rico M J Izquierdo , Holt W V , Chevret P , Lopez-Bejar M , Martinez-Nevado E , Ballesta J , Aviles M

Introduction: The zona pellucida (ZP) is an extracellular matrix that surrounds mammalian oocytes. Marsupial ZP has been considered formed by three proteins. However, the recent description of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) in the ZP of some species of eutherian (rat, human, hamster, rabbit) suggests the need for a reanalysis of the ZP composition in marsupials.Material and methods: Complementary DNA was obtained from ovaries from one Austra...